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PEPID
Subsections
Hiatal Hernia

Gastroenterology

Hiatal Hernia

Background

  1. Definition
    • Herniation of the stomach (and occasionally other abdominal organs) through the esophageal hiatus into the thoracic cavity
    • Also known as:
      • Diaphragmatic hernia
      • Hiatus hernia
  2. Synopsis
    • Acquired hernias
      • Most cases are asymptomatic
      • If present, symptoms resemble esophagitis or GERD
    • Congenital hernias
      • Usually symptomatic at birth
      • Large defects are not compatible with life unless surgically corrected

Pathophysiology

  1. Mechanism
    • Main etiologies
      • Age-related degeneration
      • Prolonged stretching of the GE junction
      • Increased intraabdominal pressure
      • Congenital (rare)
    • Possible rupture of the phrenoesophageal ligament
    • Development of hernia
    • Diaphragmatic hiatus transforms from a small fissure to a true oval opening formed by the diaphragmatic muscles
    • Exposure of esophageal mucosa to gastric acid
      • Associated with larger hernias
    • Cameron lesions
      • Small ulcerative lesions on herniated gastric mucosa
      • Found at the level of diaphragm
      • Likely due to ischemia caused by gastric wall sliding in and out of the thoracic cavity
      • May lead to GI bleeding
    • Types of acquired hiatal hernia
      • Type 1: sliding hernia (95% cases)
        • Protrusion of GE junction or gastric cardia through the esophageal hiatus
        • Phrenoesophageal ligament becomes more lax but remains intact
        • Hernia may slide in and out of thoracic cavity
          • Consequently, the size of hernia may vary
        • Frequently associated with loss of tone of the lower esophageal sphincter (LES)
      • Type 2: paraesophageal "rolling" hernia (5% cases)
        • Partial protrusion of the stomach into the thoracic cavity
        • Associated with mechanical complications (volvulus)
        • Usually due to partially damaged phrenoesophageal ligament
        • Gastric fundus "rolls" into thoracic cavity
          • Usually located to the left of distal esophagus
        • GE junction remains at the level of diaphragm
        • In extreme cases, most of the stomach may herniate into thoracic cavity
      • Type 3: mixed hernia (rare)
        • Features of type 1 and type 2
        • Usually begins as type 2 hernia
        • Sliding component develops over time
      • Type 4:
        • Protrusion of other intraabdominal organs
        • Associated with large defects of phrenoesophageal ligament
        • Herniated organs may include:
          • Stomach
          • Spleen
          • Pancreas
          • Omentum
          • Colon
          • Small intestine
  2. Etiology/Risk Factors
    • Repetitive vomiting
    • Pregnancy
    • Obesity
    • Power athletes
    • Genetic predisposition
      • Autosomal dominant inheritance has been reported in some families with type 1 hiatal hernia
      • High concordance rate in identical twins
  3. Epidemiology
    • Incidence/Prevalence
      • Acquired hiatal hernia
        • Found in 55-60% of persons aged > 50 yo
          • 9% display symptoms
        • Up to 80% of power athletes
        • Prevalence increases with age
        • Sliding hernia > paraesophageal hernia (100:1)
        • Sliding hernia
          • Males > females
        • Paraesophageal hernia
          • Females > males (4:1)
      • More common in N America and W. Europe as opposed to rural Africa
    • Mortality/Morbidity
      • Associated with:
        • GERD
        • Esophagitis
        • Diverticulosis
        • Duodenal ulcers
        • Gallstones

Diagnostics

  1. History/Symptoms
    • Acquired hernias
      • Most cases are asymptomatic
      • If present, symptoms resemble esophagitis or GERD:
        • Heartburn
        • Epigastric pain
        • Regurgitation
        • Dysphagia
        • Chest pain
        • Postprandial fullness
        • Hoarseness
  2. Physical Exam/Signs
    • No characteristic physical exam findings
      • Diagnosis largely based on history of esophagitis or GERD, and evidence provided by diagnostic imaging
      • Often diagnosed incidentally
    • Findings may include:
      • Oral cavity
        • Dental enamel erosion
        • Throat erythema
      • Auscultation
        • Bowel sounds over the left lung base
      • Palpation
        • Epigastric tenderness
    • Regurgitated food should be noted if digested or undigested
      • Undigested food may reveal different pathology (e.g., achalasia or diverticulum)
    • Rule out other etiologies
  3. Labs/Tests
    • No specific lab findings
    • CBC +Diff, CMP
      • Iron deficiency anemia may be present
        • Cameron lesions
      • WBC count
      Consider testing to rule out other conditions
  4. Imaging
    • CXR
    • Upper GI series
      • Barium contrast
      • Preferred examination for suspected hiatal hernia
      • Presence of gastric cardia 2 cm above the hiatus
      • Not required if endoscopy ordered
    • CT/MRI (View image)
      • Assess herniation of other abdominal organs
      • Indicated for equivocal cases
    • Ultrasound (abdominal)
      • Esophageal diameter of ≥ 18 mm at the diaphragm
  5. Other Tests/Criteria
    • Endoscopy
      • Upper GI
      • Allows for direct visualization of hernia and assessment of complications
    • Esophageal manometry
      • Low sensitivity, high specificity
      • Rarely performed
      • May help establish the diagnosis in conjunction with endoscopy findings
    • pH monitoring
      • Gold standard for dx of acid reflux
      • Probe placed 5 cm above GE jxn and measures amount of acid to which exposed
  6. Differential Diagnosis

Treatment

  1. Initial/Prep/Goals
    • ABCs, monitors
    • Conservative management
      • Eat 5-6 small meals per day
      • Do not lie down soon after eating
      • Sleep with head of bed elevated
      • Avoid consumption of large amounts of food
      • Avoid foods and medications that decrease LES tone
        • Calcium channel blockers (CCB)
        • Anticholinergics
        • Caffeine
        • Mint
        • Chocolate
      • Weight loss
    • Medications
      • H2 antagonists
        • Indicated for symptomatic disease (heartburn)
      • PPIs
        • Indications
          • Symptomatic disease (heartburn)
          • Esophagitis
    • Refractory cases
      • Consult gastroenterology
  2. Medical/Pharmaceutical
  3. Surgical/Procedural
    • Surgical management
      • Indications
        • Refractory symptoms
        • GI bleeding
        • Congenital hernia
        • Ulcer
        • Stricture
        • Barrett's mucosa
        • Paraesophageal hernias
          • All symptomatic pts
          • Asymptomatic large hernias in pts < 60 yo and healthy
    • Nissan fundoplication (360-degree wrap)
      • Complete wrapping of GEJ using fundus of stomach
      • 52 French bougie in place
        • Ensures approp. approx. w/o wrap being too tight
      • Dissection of short gastric vessels off the greater curvature of the stomach to mobilize the fundus
      • Phrenoesophageal membrane over left crus full dissected and crural fibers identified
      • For right crural dissection, lesser omentum is opened and right phrenoesophageal membrane mobilized
        • Note: pressure anterior and posterior vagi during dissection
        • Pentose drain is placed around the esophagus to assist mobilization and creation of the wrap
        • Wrap is created over a length of 2.5 to 3 cm using 3-4 interrupted permanent sutures
        • When wrap complete, 52 French bougie is removed, wrap is anchored to esophagus and hiatus
        • This prevents herniation and slippage
    • Partial fundoplication (Dor and Toupet)
      • Procedure of choice when esophageal motility is poor
      • 2 most common partial fundoplication are
        • Dor procedure
          • Anterior wrap
          • Performed by folding fundus over the anterior aspect of the esophagus
            • Then anchoring it to hiatus and esophagus
          • Used at times for tx of GERD
          • More commonly used in pts w/ achalasia who have undergone anterior myotomy
        • Toupet procedure
          • Posterior wrap
          • Esophageal dissection (same as Nissen), w/ mobilization of esophagus
          • Creates 220-250-degree wrap around posterior aspect of esophagus
          • Procedure of choice for motility concern
        • They involve creating a 180 to 250-degree wrap
        • Partial wrap will help prevent obstruction in esophagus when motility a concern
  4. Complications
    • GERD
    • Esophagitis
    • Barrett's esophagus
    • Esophageal stenosis
    • Strangulation / volvulus
    • GI bleeding
    • Lung collapse
    • Aspiration pneumonia
    • ENT disorders
    • Heart failure
  5. Prevention
    • Weight loss
    • Avoidance of strenuous physical activity associated with increased intraabdominal pressure

Disposition

  1. Admission Criteria
    • Congenital hernia
    • Severe clinical status
    • See also Complications
  2. Consults
    • Gastroenterology
      • Indicated for refractory cases
    • Surgery
      • Refractory cases of acquired hiatal hernia
      • Congenital diaphragmatic hernia
    • Pulmonology
      • Extra-esophageal symptoms of GERD
        • Laryngeal/pulmonary symptoms
  3. Discharge/Follow-up Instructions
    • Follow-up with primary care or gastroenterologist in 2-4 weeks

References

  1. Reddy RM, Meyers BF. Esophagus. In: Klingensmith ME, Chen LE, Glasgow SC; (eds). The Washington Manual of Surgery, 5th ed. Philadelphia, PA:Lippincott Williams & Wilkins, 2007;Chapter 8
  2. Kahrilas PJ, Kim HC, Pandolfino JE. Approaches to the diagnosis and grading of hiatal hernia. Best Pract Res Clin Gastroenterol. 2008;22(4):601-616
  3. Naunheim KS, Edwards M. Paraesophageal Hiatal Hernia. In: Shields TW, LoCicero III J, Reed CE, Feins RH; (eds). General Thoracic Surgery, 7th ed. Philadelphia, PA:Lippincott Williams & Wilkins, 2009;Chapter 155
  4. Society of American Gastrointestinal and Endoscopic Surgeons (SAGES). Guidelines for the Management of Hiatal Hernia. Available at: http://www.sages.org/publications/guidelines/guidelines-for-the-management-of-hiatal-hernia/. [Accessed June 2022]
  5. Kimer N, Schmidt PN, Krag A. Cameron lesions: an often overlooked cause of iron deficiency anaemia in patients with large hiatal hernias. BMJ Case Reports Oct 2010;2010
  6. Ferri F. Hiatal Hernia (PTG). In: Ferri F; (eds). Ferri's Clinical Advisor 2015: 5 Books in 1. Philadelphia, PA:Elsevier-Mosby, 2014;pg.571
  7. Neumeyer L, McGregor DB, Mann B. Abdominal Wall, Including Hernias. In: Lawrence PF, Bell RM, Dayton MT; (eds). Essentials of General Surgery, 4th ed. Philadelphia, PA:Lippincott Williams & Wilkins, 2005;Chapter 12
  8. Bredenoord AJ, Smout AJPM. Hiatus Hernia and Gastroesophageal Reflux Disease. In: Richter JE, Castell DO; (eds). The Esophagus, 5th ed. Oxford, UK:Wiley-Blackwell, 2012;Chapter 20
  9. Hiatal Hernia. StatPearls [Internet]. Available at: https://www.ncbi.nlm.nih.gov/books/NBK562200/. [Accessed June 2022]

Contributors

  1. Ballarin, Daniel, MD
  2. Singh, Ajaydeep, MD

Updated/Reviewed: June 2022