PEPID Connect Help
View Tutorial
Contact PEPID Support
Suggest an edit
Current tool:
Current monograph:
Hello, PEPID User
PEPID
Subsections
Eye Foreign Body and Corneal Abrasions

Ophthalmology

Eye Foreign Body and Corneal Abrasions

Background

  1. Definition
    • Eye foreign body (FB)
      • FB introduced to eye
    • Corneal abrasion
      • Eye injury that causes significant discomfort, photophobia and erythema
      • Aka scratched eye, scratched cornea
  2. Synopsis
    • Both are common eye injuries responsible for ED visits
      • Also common workplace eye injuries
    • Management consists of
      • Removal of foreign body before it induces corneal abrasion
      • Management of abrasions with anti-microbials, pain control, physical shielding (e.g., eye patch, goggles, etc.)

Pathophysiology

  1. Mechanism
    • Traumatic corneal abrasion:
      • Mechanical trauma to eye
        • Leads to abrasion defect in epithelial surface (corneal epithelium)
    • Foreign body induced:
      • Abrasions remain after removing/spontaneous dislodging corneal foreign body
      • Outer epithelial layer of cornea disrupted
      • Contact lens-induced:
        • Abrasions remain after removing over worn, improperly fitting or dirty contact lens
    • Spontaneous:
      • As a result of no immediately preceding injury/foreign body trauma
    • Low-velocity projectiles:
      • May embed in cornea
      • May be entrapped between upper eyelid & cornea
    • High-velocity projectiles:
      • May embed deeper into cornea and injure deeper structures
    • Annular "rust rings":
      • Surround a retained ferrous foreign body
      • May develop within a few hrs
    • Chemical/heat abrasions:
      • Causes burns and scarring
    • Exposure to UV radiation (see UV keratitis)
  2. Etiology/Risk Factors
    • Traumatic corneal abrasion
      • Fingernails, piece of paper/cardboard
      • Cosmetic makeup applicators, hand tools
      • Foreign body-related
      • Tree branches, workplace debris
      • Sports equipment
      • Contact lens related
      • Chemical/heat abrasions
      • Sand, other small particles
    • Spontaneous
      • Previous abrasions and defects
    • Exposure to UV radiation
      • UV light and welding arcs or sun lamps
  3. Epidemiology
    • Incidence/Prevalence
      • ED visits (8% eye injury)
        • 87% corneal abrasions
        • 3% of ED visits
        • 2% of visits in primary care clinics (eye complaints)
          • FBs responsible for 8% of these visits
      • Workplace eye injuries
        • 15 cases/1000 employees (US autoworkers)
          • 87% are corneal abrasions
      • Prevalent among contact lens wearers
      • Common in all age groups
    • Mortality/Morbidity
      • Pain, headaches
      • Blurred vision (can be permanent)
      • Blindness in affected eye
      • Foreign can continue moving outward and become an open globe injury

Diagnostics

  1. History/Symptoms
    • Excruciating sudden eye pain
    • Inability/difficulty to open the eye
      • Foreign body sensation
    • Uncomfortable to do routine things
    • Washing eye causes exacerbation of discomfort
    • +/- tearing, photophobia
    • Decreased visual acuity
    • Pain dramatically relieved by topical anesthetic
    • Surrounding eye muscle spasms
      • May cause squinting
    • Awaken in the middle of night
    • Rule out
      • Penetrating trauma
      • Infectious infiltration
    • +/- contact lenses
    • Flying/material falling into eye
    • Place of employment
    • Hobbies (working w/ wood or metal, etc)
    • History of any prior traumatic abrasion
      • Awakening middle of night with eye pain
  2. Physical Exam/Signs
    • See also eye exam in trauma
    • Begin exam w/ a penlight
      • Abnormally shaped pupil could be a sign of globe rupture
    • Topical anesthetic to facilitate exam
    • Avoid pressure on the globe
    • Note erythematous conjunctiva
    • Light sensitivity
    • Excessive lacrimation
    • Decreased visual acuity
    • If blood (hyphema), pus (hypopyon) in anterior chamber
      • Ophthalmologist examination that day
  3. Complete Eye Exam
    • Visual acuities examination
      • Right (OD), Left (OS), Both (OU):
      • Absolutely ESSENTIAL to check & examine
        • The "Vital Sign" of eye
      • May be normal if abrasion is not near
      • +/- corneal edema
    • Visual fields examination
      • Check extraocular motion
      • Evert and examine/clean under upper and lower lids
    • Fundoscopic examination
      • Examine cornea and anterior chamber with slit lamp (if avai
      • lable)
        • Note any anterior chamber cell or flare
        • Any abrasions, hypopyon, hyphema, blood, or foreign bodies
        • Note red reflex
    • Fluorescein exam
      • To confirm diagnosis after fundus exam
        • Fluorescein stains basement membrane revealing corneal lesion
      • Corneal defects - yellow-green fluorescence under woods/slit lamp
      • Be sure NO contact lenses
        • Stains them
      • Findings
        • Multiple vertical scratches (ice rink sign)
          • Suggest foreign body embedded in upper lid
          • If not already performed, evert, and examine under surface of lid
        • Streaming/flowing appearance under a defect (Seidels sign, waterfall sign)
          • Suggests corneal perforation & possible retained foreign body
        • Diffuse uptake (corneal stippling)
          • Suggests UV keratitis from welding/sunlight
  4. Imaging
    • Consider ocular radiographs or CT of orbit if suspect intraocular retained foreign body
    • Clearly document abrasion location by diagram on chart
  5. Differential Diagnosis
    • Conjunctivitis
    • Dry eye syndrome
    • Acute angle-closure glaucoma
    • Uveitis
    • Infective keratitis
      • Bacterial
      • Fungal
      • Herpetic
    • Corneal ulcer
    • Recurrent erosion syndrome

Treatment

  1. Initial/Prep/Overview
    • Offer dark room to wait in & discourage eye rubbing
      • Eye patching (avoid)
      • Topical antibiotics
      • Topical cycloplegics
    • Tetanus prophylaxis
      • Indication: penetrating eye injuries
      • NOT for corneal abrasion or foreign body
    • Symptomatic treatments
    • If corneal abrasions with no foreign body
    • If foreign body, removal plus post-op Rx (consult ophthalmology or specialist)
      • Indications: Pain, foreign body sensation, tearing, photophobia, blepharospasm, and blurred vision
      • Contraindications: MRI is strictly contraindicated if suspect metal foreign body
  2. Medical/Pharmaceutical
    • Corneal Abrasions
      • Topical antibiotics (See also: Eye anti-infectives )
        • Ointment preferred vs drops
          • Lubricating
          • Drops may sting
        • Erythromycin: 0.5 inch ribbon QID for 3-5 days
        • Sulfacetamide 10%: 0.5 inch ribbon TID to conjunctival sac, or
          • Drops: 1-3 gtt q3h for 3-5 day
        • Polymyxin B/ trimethoprim: 0.5 inch ribbon to conjunctival sac QID, or
          • Drops: 1-2 gtt QID for 3-5 days
        • Ciprofloxacin/ofloxacin: 1 gtt affected eye QID for 1 wk
        • Avoid aminoglycosides and steroids (except contact lens abrasion)
          • Gentamicin: 1-2 gtt q4h
            • Severe infection: 2 gtt q30min for 24 hrs
      • Topical cycloplegics (r/o glaucoma)
        • Reduces response to light thus pain
        • Can relieve photophobia (generally in 2 days)
        • Cyclopentolate 0.5%, 1% (short-acting - 36 hrs): 1 gtt TID for 2 days
        • Homatropine 2.5%: usually1 drop prescribed
        • Severe iritis: Atropine
        • Side effects such as difficulty w/ reading
      • Topical NSAIDs
      • Avoid eye patch, especially in contact lenses abrasions
        • No longer than 24 hrs
      • Pain control
        • NEVER discharge with topical anesthetics
        • Not recommended to use topical anesthetics > 24 hrs
          • Can prolong resolution time
        • May retard healing, potentially mask symptoms of more serious injury
        • Mild to moderate pain can be controlled w/ NSAIDs PO
    • Contact lens abrasions
      • Risk of infectious keratitis
        • Adhesion of pathogen to ocular surface/lens
        • Pathogen colonization in solutions/lens cases
        • Extended wear (during sleep)
      • Infectious pseudomonas keratitis
        • Ulcerative necrotizing corneal melting/perforation in 24 hrs
        • Permanent corneal scarring
      • Examine for corneal infiltrate (penlight)
        • Findings: white spot, opacity, ulcer
      • Never apply eye patch
      • Pseudomonal coverage (immediate ophthalmology follow-up)
  3. Surgical/Procedural (Foreign Body Removal)
    • Equipment
      • Topical sodium fluorescein
      • Topical anesthetic drops
      • Slit lamp with cobalt blue filter
        • Or Burton lamp with similar filter
      • Sterile saline
      • Sterile cotton-tipped applicators
      • Jeweler's forceps
      • 25-g needle attached to a tuberculin syringe, a bent needle tip is optional
      • Foreign body spud (consider a magnetic spud for metallic foreign bodies)
      • Rotating burr tool (Alger brush)
      • Eyelid speculum may be necessary (e.g., strong blink reflex)
    • Anesthesia
      • Place 1-2 drops of topical anesthetic into lower fornix ≥ 30 seconds before potential contact with cornea
    • Conjunctival foreign body (trapped under lid)
      • Irrigate (recommended use 18-g syringe technique)
      • Use moistened cotton swab under eyelid
      • Using swab on cornea may cause a larger abrasion
    • Superficially embedded corneal foreign body
      • Use cotton swab, spud, or specially prepared 20-22-gauge needle
        • Prepare needle by bending to approximately 45 degrees, with bevel facing inner radius of bend
        • Use needle with bevel pointing toward you (facing outward from patient eye)
        • Edge (NOT point) of bevel is used to gently lift foreign body from cornea
        • Syringe may be attached to needle for larger handle
      • Carefully dislodge & remove foreign body
      • Ophthalmological referral (for all patients)
      • Deep injury involving stroma and in visual axis
        • Requires ophthalmologic follow-up
    • Deeply embedded material
      • Refer to ophthalmologist
        • If body is small, inert, and outside of visual axis
        • Patient may choose to leave in place to minimize scarring/expense
    • Rust rings
      • May opt to not remove small rings outside of visual axis
        • This may slow healing however
      • Fresh rings are sometimes more difficult to remove
        • Consider later referral to ophthalmologist
      • ED removal - buff off the superficial corneal layer with an eye burr (i.e., Alger brush) (View image)
      • Refer to ophthalmologist, especially for injuries in visual axis
    • Retained intraocular foreign body/punctured cornea (suspected/known)
      • Emergent ophthalmology consult
      • Apply metal shield to protect eye
        • Do not apply direct pressure to globe
    • Post-Op
      • Initiate a broad-spectrum topical antibiotic no less than 4 times daily for one week
        • Larger, deeper, or central defects may require more frequent applications and longer durations
        • If habitual contact lens wearer, ensure antibiotic therapy is effective against pseudomonas
      • Pain control
        • Ophthalmic NSAIDs
          • If breakthrough pain, add NSAIDs or Acetaminophen PO
        • Schedule III controlled drugs may be necessary (rarely)
      • Amniotic membrane therapy
        • May be beneficial in reducing residual scarring while encouraging epithelial healing
      • Bandage soft contact lens
        • Relieves pain, correct vision, and reduce surface disruption associated with blinking
      • Pressure patching
        • If large concomitant corneal abrasion
  4. Complications
    • Corneal ulcers
    • Bacterial keratitis
    • Recurrent erosion syndrome
    • Traumatic iritis

Disposition

  1. Admission criteria
    • Admit with consult recommendations
  2. Consults
    • Ophthalmology
  3. Discharge/Follow-up instructions
    • Most corneal abrasions heal regardless of therapy
      • In 24-72 hrs or overnight
      • Follow-up with PCP or ophthalmologist
        • Abrasions < 3 mm - usually not necessary
        • Contact lens abrasions - daily follow-up until healed
        • Abrasions > 3 mm - require close follow-up
    • General disposition guidelines if not requiring emergent ophthalmological consult
      • D/C with instructions
        • Do not (especially if patched)
          • Drive, ride bike, skate
          • Read
          • Excessive exercise or exertion
      • D/C with superficial abrasion or rust ring not in visual axis
      • Return if increasing eye pain/vision changes
      • Do not discharge patient with topical anesthetic drops or topical steroids
      • Instruct patient not to use contact lenses until eye is healed (at least 24 hrs)
        • Caution early after fluorescein exam
        • May permanently stain lens
        • Eye rubbing decreases healing
        • If left untreated, may lead to corneal ulcers

Related Topics

References

  1. Sharma R, Brunette DD. Ophthalmology. In: Marx: Rosen's Emergency Medicine: Concepts and Clinical Practice, 8th ed. Elsevier: Philadelphia, PA, 2014;pp. 909-930
  2. Ragge NK, Easty DL. Immediate Eye Care. St. Louis MO Moseby- Year Book Inc 1990
  3. Crumpton KL, Shockley LW. Ocular trauma: a quick illustrated guide to treatment, triage, and medicolegal implications. Emerg Med Reports 1997; 18: 223-234
  4. Dua HS, Gomes JA, Singh A. Corneal epithelial wound healing. Br J Ophthalmol. May 1994;78(5):401-408
  5. Lang J, Rah MJ. Adverse corneal events associated with corneal reshaping: a case series. Eye Contact Lens. Oct 2004;30(4):231-3; discussion 242-243
  6. Trad MJ. Pressure patching indicated in few cases of traumatic corneal abrasions. Primary Care Optometry News 9. September 2004;36-37
  7. Benson WH, Snyder IS, Granus V, Odom JV, Macsai MS. Tetanus prophylaxis following ocular injuries. J Emerg Med. Nov-Dec 1993;11(6):677-683
  8. Brown MD, Cordell WH, Gee AS. Do ophthalmic nonsteroidal anti-inflammatory drugs reduce the pain associated with simple corneal abrasion without delaying healing? Ann Emerg Med. Oct 1999;34(4 Pt 1):526-534
  9. Carley F, Carley S. Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Mydriatics in corneal abrasion. Emerg Med J. Jul 2001;18(4):273
  10. Groden LR, White W. Porcine collagen corneal shield treatment of persistent epithelial defects following penetrating keratoplasty. CLAO J. Apr-Jun 1990;16(2):95-97
  11. Hulbert MF. Efficacy of eyepad in corneal healing after corneal foreign body removal. Lancet. Mar 16 1991;337(8742):643
  12. Weaver CS, Terrell KM. Evidence-based emergency medicine. Update: do ophthalmic nonsteroidal anti-inflammatory drugs reduce the pain associated with simple corneal abrasion without delaying healing? Ann Emerg Med. Jan 2003;41(1):134-140
  13. Stapleton F, Dart J, Minassian D. Nonulcerative complications of contact lens wear. Relative risks for different lens types. Arch Ophthalmol. Nov 1992;110(11):1601-1606
  14. Corneal Foreign Body. StatPearls [Internet]. Available at: https://www.ncbi.nlm.nih.gov/books/NBK536977/. [Accessed November 2023]
  15. Cornea Foreign Body Removal. StatPearls [Internet]. Available at: https://www.ncbi.nlm.nih.gov/books/NBK554478/. [Accessed November 2023]
  16. Corneal Abrasion. StatPearls [Internet]. Available at: https://www.ncbi.nlm.nih.gov/books/NBK532960/. [Accessed November 2023]

Contributor(s)

  1. Lo, Bruce, MD, FAAEM
  2. Singh, Ajaydeep, MD

Updated/Reviewed: November 2023